PEGylated Protein Drugs: Basic Science and Clinical Applications (Milestones in Drug Therapy) |  | Creator: Francesco M. Veronese
Publisher: Birkhäuser Basel
Category: Book
List Price: $189.00
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Seller: SuperBookDeals-
Sales Rank: 1,966,163
Languages: English (Unknown), English (Original Language), English (Published)
Media: Hardcover
Edition: 1
Pages: 297
Number Of Items: 1
Shipping Weight (lbs): 1.9
Dimensions (in): 9.2 x 6.6 x 0.8
ISBN: 3764386789
EAN: 9783764386788
ASIN: 3764386789
Publication Date: October 23, 2009
Availability: Usually ships in 1-2 business days
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Product Description
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
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